PRF Hair Restoration: What You Need to Know
Dr. Blane Schilling, MD
Resident Medical Reviewer Β· Family Medicine Physician and Integrative Wellness Specialist
Dr. Blane Schilling, MD is a family medicine physician and integrative wellness specialist with 30 years of clinical experience. He reviews medically sensitive articles for medical accuracy, safety context, contraindications, evidence quality, and practical reader risk across supplements, procedures, treatments, and wellness topics.
Last Updated: February 2026
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PRF vs PRP: What's the Difference?
PRF is an evolution of PRP therapy. While PRP uses an anticoagulant and centrifuges blood at high speed, PRF uses a slower spin without additives, creating a fibrin matrix that releases growth factors over a longer period. This sustained release may provide superior results.
How It Works
A small blood sample is drawn and processed in a specialized centrifuge. The resulting PRF matrix is injected into areas of thinning. The growth factors stimulate dormant follicles and improve blood supply to the scalp.
Expected Results
Most patients see noticeable improvement after 3-4 sessions spaced 4-6 weeks apart. Results include reduced shedding, improved hair thickness, and reactivation of dormant follicles. Maintenance sessions every 6-12 months are recommended.
Cost
Individual PRF sessions cost $600-$1,800 in the USA. A full treatment course of 3-4 sessions ranges from $1,800-$6,000. Some clinics offer package pricing.
FAQ
Is PRF better than PRP for hair loss?
Early research suggests PRF may offer longer-lasting growth factor release than PRP, potentially improving outcomes. However, both are effective treatments.
How many PRF sessions do I need?
A typical treatment course involves 3-4 sessions spaced 4-6 weeks apart, followed by maintenance sessions every 6-12 months.
Does PRF hurt?
Most patients experience minimal discomfort. Numbing cream is applied to the scalp before treatment, and the injections feel like mild pinches.
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